Our approach- testing, strain selection, licensing

The Science

Bacteria have a reputation for causing disease, so the idea of tossing down a few billion a day for your health might seem — literally and figuratively — hard to swallow. But a growing body of scientific evidence suggests that you can treat and even prevent some illnesses with foods and supplements containing certain kinds of live bacteria.
Commonly referred to as microflora, good and bad bacteria need to be balanced for optimal health. Good bacteria, the kinds found in probiotic supplements and fermented foods, help synthesise key nutrients, help the body digest fibre, support immune function by stimulating it and keep bad bacteria at bay.

A host of other factors can disturb the ratio of good-to-bad bacteria – food choices, stress, poor sleep, pollution, disease, medications, antibiotics. An imbalanced gut flora is referred to as ‘dysbiosis’ and can lead to many gut-specific symptoms beyond the gut.

Probiotics are gut-dwelling bacteria that keep pathogens (harmful microorganisms) in check, aid digestion and nutrient absorption, and contribute to immune function.

It is important to make sure that the probiotic supplement can reach its site of action and the strains contained are backed by research showing a beneficial effect

Our Strains

L. reuteri 

Inhibits the colonization of pathogenic microbes and remodel the commensal microbiota composition in the host.
Reduce the production of pro-inflammatory cytokines while promoting regulatory T cell development and function.
Bearing the ability to strengthen the intestinal barrier, the colonization of L. reuteri may decrease the microbial translocation from the gut lumen to the tissues

L. reuteri
L. acidophilus

L. acidophilus 

This bacteria helps the digestive system break down sugars, such as lactose, into lactic acid.
Help protect against harmful germs.
This is because they create an acidic environment that the germs do not like.
May lower the risk of getting depression or even help treat symptoms in people with depression.

L. plantarum

Good adaptation and adhesion ability in the gastro-intestinal tract and the potential to affect host health through various beneficial activities, e.g., antimicrobial, antioxidative, antigenotoxic, anti-inflammatory and immunomodulatory, in several in vitro and in vivo studies.
Stimulate your digestive system, fight off disease-causing bacteria, and help your body to produce vitamins.
Treat or prevent specific health problems, such as seasonal allergies and irritable bowel syndrome.

L. plantarum
L. casei

L. casei

​​The group have been extensively researched with regard to stress responses.
Produce many bioactive metabolites which can confer host benefits.

L. rhamnosus

Has the ability to counter pathogenic bacteria and fungi in the urogenital tract.
An ability to prevent recurrent urinary tract infections in post-menopausal women.

L. rhamnosus
L. fermentum

L. fermentum 

Reduces cholesterol and boosts immunity.
Particularly beneficial for dealing with issues more prevalent in women, like yeast infections and UTIs.
May assist in reducing the development of obesity by modifying the way energy is handled within the host.

Bifidobacterium bifidum

They may help with diarrhea, constipation, and other intestinal disorders.
Suppresses Gut Inflammation Caused by Repeated Antibiotic Disturbance

Bifidobacterium bifidum

Clinical Studies

Avershina, E., Lundgård, K., Sekelja, M., Dotterud, C., Storrø, O., & Øien, T. et al. (2016). Transition from infant- to adult-like gut microbiota. Environmental Microbiology, 18(7), 2226-2236. https://doi.org/10.1111/1462-2920.13248

Bajinka, O., Tan, Y., Abdelhalim, K., Özdemir, G., & Qiu, X. (2020). Extrinsic factors influencing gut microbes, the immediate consequences and restoring eubiosis. AMB Express, 10(1). https://doi.org/10.1186/s13568-020-01066-8

Carding, S., Verbeke, K., Vipond, D., Corfe, B., & Owen, L. (2015). Dysbiosis of the gut microbiota in disease. Microbial Ecology In Health & Disease, 26(0).https://doi.org/10.3402/mehd.v26.26191

Ghoddusi, H., & Tamime, A. (2014). MICROFLORA OF THE INTESTINE | Biology of Bifidobacteria. Encyclopedia Of Food Microbiology, 639-645. https://doi.org/10.1016/b978-0-12-384730-0.00208-1

Hill, D., Sugrue, I., Tobin, C., Hill, C., Stanton, C., & Ross, R. (2018). The Lactobacillus casei Group: History and Health Related Applications. Frontiers In Microbiology, 9. https://doi.org/10.3389/fmicb.2018.02107

Hoover, D. (2014). Bifidobacterium. Encyclopedia Of Food Microbiology, 216-222. https://doi.org/10.1016/b978-0-12-384730-0.00033-1

Hosseini Nezhad, M., Hussain, M., & Britz, M. (2014). Stress Responses in ProbioticLactobacillus casei. Critical Reviews In Food Science And Nutrition, 55(6), 740-749. https://doi.org/10.1080/10408398.2012.675601

Jochum, L., & Stecher, B. (2020). Label or Concept – What Is a Pathobiont?. Trends In Microbiology, 28(10), 789-792. https://doi.org/10.1016/j.tim.2020.04.011

Kaźmierczak-Siedlecka, K., Daca, A., Folwarski, M., Witkowski, J., Bryl, E., & Makarewicz, W. (2020). The role of Lactobacillus plantarum 299v in supporting treatment of selected diseases. Central European Journal Of Immunology, 45(4), 488-493. https://doi.org/10.5114/ceji.2020.101515

María Remes-Troche, J., Coss-Adame, E., Ángel Valdovinos-Díaz, M., Gómez-Escudero, O., Eugenia Icaza-Chávez, M., & Antonio Chávez-Barrera, J. et al. (2020). Lactobacillus acidophilus LB: a useful pharmabiotic for the treatment of digestive disorders. Therapeutic Advances In Gastroenterology, 13, 175628482097120. https://doi.org/10.1177/1756284820971201

Molnar-Gabor, D., Hederos, M., Bartsch, S., & Vogel, A. (2019). Emerging Field - Synthesis of Complex Carbohydrates. Case Study on HMOs. Industrial Enzyme Applications, 179-201. https://doi.org/10.1002/9783527813780.ch2_5

Mu, Q., Tavella, V., & Luo, X. (2018). Role of Lactobacillus reuteri in Human Health and Diseases. Frontiers In Microbiology, 9. https://doi.org/10.3389/fmicb.2018.00757

Rodríguez-Sojo, M., Ruiz-Malagón, A., Rodríguez-Cabezas, M., Gálvez, J., & Rodríguez-Nogales, A. (2021). Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights. Nutrients, 13(3), 1016. https://doi.org/10.3390/nu13031016

Turroni, F., Duranti, S., Milani, C., Lugli, G., van Sinderen, D., & Ventura, M. (2019). Bifidobacterium bifidum: A Key Member of the Early Human Gut Microbiota. Microorganisms, 7(11), 544. https://doi.org/10.3390/microorganisms7110544

Wallace, C., & Milev, R. (2017). The effects of probiotics on depressive symptoms in humans: a systematic review. Annals Of General Psychiatry, 16(1). https://doi.org/10.1186/s12991-017-0138-2

Won, G., & Lee, J. (2017). Salmonella Typhimurium, the major causative agent of foodborne illness inactivated by a phage lysis system provides effective protection against lethal challenge by induction of robust cell-mediated immune responses and activation of dendritic cells. Veterinary Research, 48(1). https://doi.org/10.1186/s13567-017-0474-x

ZAMBERLIN, Š., DOLENČIĆ ŠPEHAR, I., KELAVA, N., & SAMARŽIJA, D. (2012). Probiotic bacterium Lactobacillus rhamnosus: beneficial and adverse effects on human health. https://www.researchgate.net/publication/273769199_Probiotic_bacterium_Lactobacillus_rhamnosus_Beneficial_and_a_dverse_effects_on_human_health.